As mentioned in an earlier blog, colistin, named the 'last resort' was rendered obsolete as bacteria developed resistance. This was found in China but has now been identified in bacteria from Denmark.This means that for polymxins, that colistin was, there is no great antibiotic. This is a incredibly unsettling notion. The infections which colistin was used for are now being referred to as 'pan resistant' this is used for bacteria with genes that defeat all antibiotics now available. The gene , mcr - 1, when identified was compared to the Danish database of bacterial DNA. It was found one person had an infection was the resistance and five poultry samples had bacteria with resistance. The worrying thing about this discovery was that all the bacteria he found to be resistant to colistin was also resistant to penicillin and cephalosporins. This means that the amount of antibiotics a bacteria could be resistant could be practically infinite, this is how 'super bugs' are formed and someone could get infected but antibiotics would be obsolete. Researchers all over the globe are checking to see if it has infected certain places, it has not yet been found in America. Having researched Clostridium Difficile a fairly hardy bacteria that is resistant to multiple antibiotics, I feel that if it wasn't already resistane is a serious issue.
https://www.newscientist.com/article/dn28633-resistance-to-last-resort-antibiotic-has-now-spread-across-globe/